Ellagic acid glycosides with hepatoprotective activity from traditional Tibetan medicine Potentilla anserina
Two new gallic acid glycosides, potentillanosides G ( 1 ) and H ( 2 ), were newly isolated from the methanol extract of the tuberous roots of Potentilla anserina (Rosaceae), together with a known compound, ellagic acid 3- O -α- l -rhamnopyranoside ( 3 ). Their structures were elucidated on the basis...
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| Veröffentlicht in: | Journal of natural medicines 2018, Vol.72 (1), p.317-325 |
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| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | Two new gallic acid glycosides, potentillanosides G (
1
) and H (
2
), were newly isolated from the methanol extract of the tuberous roots of
Potentilla anserina
(Rosaceae), together with a known compound, ellagic acid 3-
O
-α-
l
-rhamnopyranoside (
3
). Their structures were elucidated on the basis of chemical and physicochemical evidence. Among the constituents, potentillanoside H (
2
, IC
50
= 99.5 μM) was found to show hepatoprotective activity. |
|---|---|
| ISSN: | 1340-3443 1861-0293 |
| DOI: | 10.1007/s11418-017-1137-y |