Prevalence of KIR haplotypes and association with mortality in a cohort of critical care patients

Prevalence of KIR haplotypes and association with mortality in a cohort of critical care patients

Objectives: Natural killer (NK) is part of innate immune system, and its activity is regulated by activating and inhibitory signals transduced by killer cell immunoglobulin-like receptors (KIsR). Methods: DNA samples of 271 Caucasoid critical care patients of both sexes, ages ranging from 14 to 94 y...

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Veröffentlicht in:Journal of critical care 2017-12, Vol.42, p.396-396
Hauptverfasser: de Oliveira, Luciana Mello, Portela, Pamela, Dias, Fernando Suparregui, Alho, Clarice Sampaio, Dal-Pizzol, Felipe, Jobim, Luiz Fernando, Jobim, Mariana, Roesler, Rafael
Format: Artikel
Sprache:eng
Schlagworte:
Critical care
Haplotypes
Health risks
Immune system
Immunoglobulins
Mortality
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Zusammenfassung:Objectives: Natural killer (NK) is part of innate immune system, and its activity is regulated by activating and inhibitory signals transduced by killer cell immunoglobulin-like receptors (KIsR). Methods: DNA samples of 271 Caucasoid critical care patients of both sexes, ages ranging from 14 to 94 years old, admitted to the Intensive Care Unit of São Lucas Hospital, Pontifical Catholic University of Rio Grande do Sul, between 2004 and 2010 were analyzed.
ISSN:0883-9441
1557-8615
DOI:10.1016/j.jcrc.2017.09.081