Septic arthritis with Listeria monocytogenes during low‐dose methotrexate

Jansen TLThA, van Heereveld HAEM, Laan RFLM, Barrera P, van de Putte LBA (University Hospital Nijmegen, Nijmegen, The Netherlands). Septic arthritis with Listeria monocytogenes during low‐dose methotrexate (Case Report). J Intern Med 1998; 244: 87–90. We describe a 22‐year‐old female with systemic lupus erythematosus and lymphopenia, who developed septic arthritis of the right knee with Listeria monocytogenes type 1/2 A, whilst on low‐dose methotrexate (MTX). So far, septic arthritis due to this microorganism has been reported in two other patients treated with low‐dose MTX, one having rheumatoid arthritis and the other psoriatic arthritis. No reports exist on patients treated with other cytotoxic antirheumatic therapies.