Hiyama cross‐coupling reaction using Pd(II) nanocatalyst immobilized on the surface of Fe3O4@SiO2

We report a simple process for the synthesis of Fe3O4@SiO2/APTMS (APTMS = 3‐aminopropyltrimethoxysilane) core–shell nanocatalyst support. The new nanocatalyst was prepared by stabilization of Pd(cdha)2 (cdha = bis(2‐chloro‐3,4‐dihydroxyacetophenone)) on the surface of the Fe3O4@SiO2/APTMS support. The structure and composition of this catalyst were characterized using various techniques. An efficient method was developed for the synthesis of a wide variety of biaryl compounds via fluoride‐free Hiyama cross‐coupling reactions of aryl halides with arylsiloxane, with Fe3O4@SiO2/APTMS/Pd(cdha)2 as the catalyst under reaction conditions. This methodology can be performed at 100°C through a simple one‐pot operation using in situ generated palladium nanoparticles. High catalytic activity, quick separation of catalyst from products using an external magnetic field and use of water as green solvent are attributes of this protocol. A new nanocatalyst was prepared by stabilization of Pd(cdha)2 in the surface of Fe3O4@SiO2/APTMS support. High yields of products, as well as high stereoselectivity, high speed of the reaction and use of water as the solvent to additional eco‐friendly attribute are important features in the fluoride‐free Hiyama cross coupling reaction.