Long-term ingestion of a fermented soybean-derived Touchi-extract with (alpha)-glucosidase inhibitory activity is safe and effective in humans with borderline and mild type-2 diabetes

Water-extracted Touchi, a traditional Chinese food, exerts a strong inhibitory activity against rat intestinal alpha-glucosidase in foodstuffs, and Touchi-extract (TE) has been shown to have an antihyperglycemic effect in rats and humans after a single oral administration. The antiglycemic effects and safety of long-term ingestion of TE in subjects with borderline and mild type-2 diabetes were examined.