Fe and Ni-catalyzed electrochemical perfluoroalkylation of C—H bonds of coumarins

A new method for the preparation of perfluoroalkylcoumarins in a single step is developed. The compounds are prepared via electrocatalytic reduction of a 1 : 1 mixture of an aromatic compound (coumarin, 6-methylcoumarin, and 7-methylcoumarin) and a fluoroalkylating reagent under mild conditions (room temperature, normal pressure) using [bipyFe II ] or [bipyNi II ] complexes as catalysts. The developed method makes it possible to obtain perfluoroalkylcoumarins in high yields and 100% conversion of the fluoroalkylating reagent.