Synthesis and Antimicrobial Activity of Glucuronosyl Derivatives of Steviolbioside from Stevia rebaudiana

Synthesis and Antimicrobial Activity of Glucuronosyl Derivatives of Steviolbioside from Stevia rebaudiana

Glucuronosyl derivatives of the glycoside steviolbioside from Stevia rebaudiana were synthesized for the first time. Steviolbioside exhibited selective bacteriostatic and bactericidal activity against S. aureus ATCC 209p with minimum inhibitory concentration (MIC) of 62.5 μg/mL, which corresponded t...

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Veröffentlicht in:Chemistry of natural compounds 2017-11, Vol.53 (6), p.1107-1111
Hauptverfasser: Sharipova, R. R., Andreeva, O. V., Strobykina, I. Yu, Voloshina, A. D., Strobykina, A. S., Kataev, V. E.
Format: Artikel
Sprache:eng
Schlagworte:
Antibiotics
Derivatives
Medicine
Organic Chemistry
Pharmacy
Plant Sciences
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Zusammenfassung:Glucuronosyl derivatives of the glycoside steviolbioside from Stevia rebaudiana were synthesized for the first time. Steviolbioside exhibited selective bacteriostatic and bactericidal activity against S. aureus ATCC 209p with minimum inhibitory concentration (MIC) of 62.5 μg/mL, which corresponded to the activity of the antibiotic chloramphenicol.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-017-2211-0