All naturally occurring autoantibodies against the NMDA receptor subunit NR1 have pathogenic potential irrespective of epitope and immunoglobulin class
Autoantibodies of the IgG class against N -methyl- d -aspartate-receptor subunit NR1 (NMDAR1) were first described in anti-NMDAR encephalitis and seen as disease indicators. Recent work on together over 5000 individuals challenged this exclusive view by showing age-dependently up to >20% NMDAR1-a...
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Veröffentlicht in: | Molecular psychiatry 2017-12, Vol.22 (12), p.1776-1784 |
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Sprache: | eng |
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