Back Cover: Remote Regulation of Membrane Channel Activity by Site‐Specific Localization of Lanthanide‐Doped Upconversion Nanocrystals (Angew. Chem. Int. Ed. 11/2017)

Back Cover: Remote Regulation of Membrane Channel Activity by Site‐Specific Localization of Lanthanide‐Doped Upconversion Nanocrystals (Angew. Chem. Int. Ed. 11/2017)

Spatiotemporal regulation of membrane channel activity in living systems has been achieved by irradiation with near‐IR light (λ=808 nm), as reported by B. Xing, G. Liu, and co‐workers in their Communication on page 3031 ff. Metabolic glycan biosynthesis is used to attach lanthanide‐doped upconversio...

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Veröffentlicht in:Angewandte Chemie International Edition 2017-03, Vol.56 (11), p.3110-3110
Hauptverfasser: Ai, Xiangzhao, Lyu, Linna, Zhang, Yang, Tang, Yanxia, Mu, Jing, Liu, Fang, Zhou, Yixi, Zuo, Zhenghong, Liu, Gang, Xing, Bengang
Format: Artikel
Sprache:eng
Schlagworte:
Biosynthesis
Cell surface
Channel gating
click chemistry
Crystals
Glycan
ion channels
Irradiation
lanthanides
Localization
Nanocrystals
Upconversion
Workers
Zebrafish
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Zusammenfassung:Spatiotemporal regulation of membrane channel activity in living systems has been achieved by irradiation with near‐IR light (λ=808 nm), as reported by B. Xing, G. Liu, and co‐workers in their Communication on page 3031 ff. Metabolic glycan biosynthesis is used to attach lanthanide‐doped upconversion nanocrystals (UCNs) to the cell surface through copper‐free click cyclization. Cation influx can be controlled by irradiation and membrane‐associated activities manipulated in living cells and zebrafish.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201701355