Synthesis and Insecticidal Activity of Novel Thiazole Acrylonitrile Derivatives
A series of novel thiazole acrylonitrile derivatives was designed and synthesized utilizing NC‐510 as a precursor. Their structures were characterized by NMR spectrometry, MS, and elemental analysis. The results of bioassay indicated that some of these title compounds exhibited 100% mortality at 50 ...
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Veröffentlicht in: | Journal of heterocyclic chemistry 2017-11, Vol.54 (6), p.3395-3402 |
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Hauptverfasser: | , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | A series of novel thiazole acrylonitrile derivatives was designed and synthesized utilizing NC‐510 as a precursor. Their structures were characterized by NMR spectrometry, MS, and elemental analysis. The results of bioassay indicated that some of these title compounds exhibited 100% mortality at 50 mg/L against Aphis fabae. In particular, the compound 11c displayed the best activity: Its LC50 value achieved 1.45 mg/L, and its insecticidal potency is comparable with that of NC‐510. |
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ISSN: | 0022-152X 1943-5193 |
DOI: | 10.1002/jhet.2961 |