Relaxant effect of Cuminum cyminum on guinea pig tracheal chains and its possible mechanism(s)
OBJECTIVE: To examine the relaxant effects of the macerated and aqueous extracts of Cuminum cyminum on the tracheal chains of guinea pig. MATERIALS AND METHODS: The relaxant effects of cumulative concentrations of macerated and aqueous extracts (0.25, 0.5, 0.75 and 1.0 g%) in comparison with salin...
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| Veröffentlicht in: | Indian journal of pharmacology 2005-03, Vol.37 (2), p.111 |
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| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | OBJECTIVE: To examine the relaxant effects of the macerated and
aqueous extracts of Cuminum cyminum on the tracheal chains of
guinea pig. MATERIALS AND METHODS: The relaxant effects of cumulative
concentrations of macerated and aqueous extracts (0.25, 0.5, 0.75 and
1.0 g%) in comparison with saline and theophylline (0.25, 0.5, 0.75,
and 1.0 mM) were examined on pre-contracted tracheal chains of guinea
pigs under different conditions. RESULTS: In Group 1 experiments
(contracted by KCl) only the last two concentrations of theophylline
and the highest concentration of macerated extract showed significant
relaxant effect compared to that of saline (P |
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| ISSN: | 0253-7613 1998-3751 |
| DOI: | 10.4103/0253-7613.15111 |