Cutaneous Toxicities From Transplantation‐Related Medications

Despite the abundance of information on cutaneous malignancies associated with solid organ transplantation in the transplant literature, there is limited information regarding nonmalignant skin changes after transplantation. There are numerous skin toxicities secondary to immunosuppressive and other...

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Veröffentlicht in:American journal of transplantation 2017-11, Vol.17 (11), p.2782-2789
Hauptverfasser: Ilyas, M., Colegio, O. R., Kaplan, B., Sharma, A.
Format: Artikel
Sprache:eng
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Zusammenfassung:Despite the abundance of information on cutaneous malignancies associated with solid organ transplantation in the transplant literature, there is limited information regarding nonmalignant skin changes after transplantation. There are numerous skin toxicities secondary to immunosuppressive and other transplant‐related medications that can vary in presentation, severity, and prognosis. To limit associated morbidity and mortality, solid organ transplant recipient care providers should effectively identify and manage cutaneous manifestations secondary to drug toxicity. Toxicities from the following transplant‐related medications will be discussed: antithymocyte globulins, systemic steroids, cyclosporine, tacrolimus, azathioprine, mycophenolate mofetil, mammalian target of rapamycin inhibitors sirolimus and everolimus, basiliximab and daclizumab, belatacept, and voriconazole. The authors review cutaneous toxicities caused by transplant‐related medications in solid organ transplant recipients.
ISSN:1600-6135
1600-6143
DOI:10.1111/ajt.14337