Hippocampal and Amygdalar Volumes in Breast Cancer Survivors with Posttraumatic Stress Disorder

Although smaller hippocampi and amygdalae were found in cancer survivors with intrusions, associations between cancer-related posttraumatic stress disorder (PTSD) and these volumes are unknown. The authors performed MRI volumetric analyses of these regions in 15 cancer survivors with PTSD, 15 cancer...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The journal of neuropsychiatry and clinical neurosciences 2008-07, Vol.20 (3), p.302-308
Hauptverfasser: Hara, Eriko, Matsuoka, Yutaka, Hakamata, Yuko, Nagamine, Mitsue, Inagaki, Masatoshi, Imoto, Shigeru, Murakami, Koji, Kim, Yoshiharu, Uchitomi, Yosuke
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Although smaller hippocampi and amygdalae were found in cancer survivors with intrusions, associations between cancer-related posttraumatic stress disorder (PTSD) and these volumes are unknown. The authors performed MRI volumetric analyses of these regions in 15 cancer survivors with PTSD, 15 cancer survivors without PTSD, and 15 healthy comparison subjects. The authors also examined the correlation between PTSD symptom scores of the Impact of Event Scale and these volumes in the PTSD group. These volumes were not significantly different among the groups, but the intrusion score was inversely associated with the hippocampal volume. Results suggest intrusions, not PTSD diagnosis, might be associated with hippocampal volume.
ISSN:0895-0172
1545-7222
DOI:10.1176/jnp.2008.20.3.302