Simultaneous Determination of Famotidine and Dicyclomine HCl in combined Tablet Dosage form by UV-Spectrophotometer

Stress testing of a drug substance can help in turns to establish the degradation pathways and the intrinsic stability of the molecule.16 The quality of the finished product is very important from the point of view of its safety, acceptability and efficacy. [...]stability is considered as one of the most important criteria in pharmaceutical quality control as stable preparations would promise delivery of the drug to the patient. [...]these solutions were diluted with methanol to get 20gg/ml of FAM and 10gg/ml of DIL and absorbance was measured at 292 and 218 nm for FAM and DIL, respectively. 5.2. [...]these solutions were diluted methanol to get 20gg/ml of FAM and 10gg/ml of DIL and absorbance was measured at 292 and 218 nm for FAM and DIL, respectively. [...]absorbance of sample was compared with standard absorbance and percent degradation was calculated. 5.3. [...]absorbance of sample was compared with standard absorbance and percent degradation was calculated. 5.4. [...]absorbance of sample was compared with standard absorbance and percent degradation was calculated. 5.5. [...]absorbance of sample was compared with standard absorbance and percent degradation was calculated. 5.6. [...]absorbance of sample was compared with standard absorbance and percent degradation was calculated. 5.7. [...]absorbance of sample was compared with standard absorbance and percent degradation was calculated. 6. [...]it can be conveniently used as tool for quality control analysis of Famotidine and Dicyclomine HCl in combine pharmaceutical solid tablet formulations.