Alum as an efficient catalyst for the multicomponent synthesis of functionalized piperidines

Alum as an efficient catalyst for the multicomponent synthesis of functionalized piperidines

An effective approach to the synthesis of functionalized piperidines via a one-pot multicomponent reaction of aniline, β -ketoester and aldehyde in the presence of alum as an efficient catalyst has been reported. The present procedure offers advantages such as simple workup, short reaction time and...

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Veröffentlicht in:Research on chemical intermediates 2017-11, Vol.43 (11), p.6099-6114
Hauptverfasser: Kaur, Ramneet, Gupta, Annah, Kapoor, Kamal K.
Format: Artikel
Sprache:eng
Schlagworte:
Alum
Aniline
Catalysis
Catalysts
Chemical synthesis
Chemistry
Chemistry and Materials Science
Inorganic Chemistry
Physical Chemistry
Reaction time
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Zusammenfassung:An effective approach to the synthesis of functionalized piperidines via a one-pot multicomponent reaction of aniline, β -ketoester and aldehyde in the presence of alum as an efficient catalyst has been reported. The present procedure offers advantages such as simple workup, short reaction time and offers rapid access to a variety of functionalized piperidines.
ISSN:0922-6168
1568-5675
DOI:10.1007/s11164-017-2979-3