A one-pot multi-component reaction for the facile synthesis of some novel 2-aryl thiazolidinones bearing benzimidazole moiety using La(NO3)3·6H2O as an efficient catalyst

A series of new derivatives of 3-benzimidazolyl-2-aryl thiazolidinones, 4a–j are synthesized via a rapid, one-pot, three-component reaction by using La(NO 3 ) 3 ·6H 2 O as an efficient catalyst from the reaction of 2-aminobenzimidazole, aromatic aldehydes and thioglycolic acid in ethanol at room temperature. These new compounds were characterized by IR, 1 H, 13 C NMR and mass spectroscopies. An inexpensive and available catalyst, short reaction time, easy workup, good to excellent yields and nontoxic solvent are the advantages of this reaction.