Comparison of sleep in hypothyroid patients with normal controls

Exclusion Criteria Nightshift workers with irregular sleep routine, diabetes mellitus, hypertension, anemia, renal failure, neurological and psychiatric disorders, substance abuse, gastroesophageal reflux disease, ear, nose, and throat T disorders, and cardiopulmonary disorders were excluded from the study. Other studies relating to the current work show increased sleep latency, reduced total sleep time, increased REM density, and REM duration with reduction in slow-wave sleep (SWS) in few patients with clinical hyperthyroidism:[14] reduced sleep efficiency, low delta sleep, short REM latency, and high REM density in one case of thyrotoxicosis;[15] higher percentage of SWS during hyperthyroid state as compared to sleep structure, once the thyroid hormone levels had returned to normal;[16] very low SWS in patients with hypothyroidism;[17] and 6 clinical hypothyroid patients with increase in sleep Stage II and reduction of SWS. [23] This study substantiates that hypothyroid patients suffer from sleep disturbance. [...]the inhibitory effect of sleep on TSH is lost aggravating the pathology to a greater extent. Sleep efficiency percentage in PSG can be considered as an indirect marker of sleep quality. [...]understanding the architecture of sleep, endogenous causes of sleep disruption, identifying and treating the underlying deficiency, will go a long way in helping the participants attain the quantity and quality of sleep needed.