Fluorescence in situ hybridization studies: break apart or not?

Sir, We would like to share our experience with acute promyelocytic leukemia (APML) molecular cytogenetic studies. Recent debate regarding interpretation of FISH (Fluorescence in situ hybridization) with BCR/ABL (ES) probe for detection of der(9q) deletion in t (9;22)(q34;q11.2) published in the jou...

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Veröffentlicht in:Indian journal of human genetics 2004-01, Vol.10 (1), p.26
Hauptverfasser: Bakshi, Sonal R, Brahmbhatt, Manisha M, Trivedi, Pina J, Rawal, Shwetal M, Kakadia, Purvi M, Bhatt, Samarth S
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Sprache:eng
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Zusammenfassung:Sir, We would like to share our experience with acute promyelocytic leukemia (APML) molecular cytogenetic studies. Recent debate regarding interpretation of FISH (Fluorescence in situ hybridization) with BCR/ABL (ES) probe for detection of der(9q) deletion in t (9;22)(q34;q11.2) published in the journal Cancer Genetics and Cytogenetics[1],[2] was interesting for the cancer cytogenetics community using commercially available FISH probes.
ISSN:0971-6866
1998-362X