Review on in-situ nasal gel drug delivery system

[...]are the nasal vasculature shows cyclical changes of congestion giving rise to the nasal cycle. [...]broad ranges of metabolic enzymes are present in the nasal mucosa. [...]pathological conditions like rhinitis, common cold can also affect absorption of drugs from nasal cavity and pH of nasal ca...

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Veröffentlicht in:Research journal of pharmacy and technology 2017, Vol.10 (6), p.1870
Hauptverfasser: Saudagar, R. B., Kulkarni, Mita M.
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container_title Research journal of pharmacy and technology
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creator Saudagar, R. B.
Kulkarni, Mita M.
description [...]are the nasal vasculature shows cyclical changes of congestion giving rise to the nasal cycle. [...]broad ranges of metabolic enzymes are present in the nasal mucosa. [...]pathological conditions like rhinitis, common cold can also affect absorption of drugs from nasal cavity and pH of nasal cavity also affects permeation of drug. [...]an adequate formulation buffer capacity may be required to maintain the pH. У Osmolarity: Drug absorption can be affected by tonicity of the formulation.
doi_str_mv 10.5958/0974-360X.2017.00328.6
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subjects Anatomy & physiology
Bioavailability
Brain research
Chemical bonds
Drug delivery systems
Drug dosages
Drug therapy
Metabolism
Metabolites
Molecular weight
Nose
Patient compliance
Permeability
Pharmaceutical sciences
Pharmacy
Physiology
title Review on in-situ nasal gel drug delivery system
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