Deuteration of Hyperpolarized 13C‐Labeled Zymonic Acid Enables Sensitivity‐Enhanced Dynamic MRI of pH

The front cover artwork is provided by the groups of Dr. Christoph Scheurer, Prof. Axel Haase, Prof. Steffen J. Glaser, Prof. Markus Schwaiger and Dr. Franz Schilling from Technical University of Munich. The image shows deuterated zymonic acid, its pH‐sensitive 13C NMR resonances and examples of how this sensor can be used to non‐invasively image pH both in vitro and in vivo. Read the full text of the article at 10.1002/cphc.201700779. “Deuteration significantly prolongs the spin lattice relaxation constant of hyperpolarized 13C zymonic acid, which is an accurate chemical‐shift‐based pH biosensor for in vitro and in vivo applications…” This and more about the story behind the front cover can be found in the Communication at 10.1002/cphc.201700779.