Protective role of prostaglandin E1 analog in indomethacin-induced deterioration in acute respiratory distress syndrome in rats

Protective role of prostaglandin E1 analog in indomethacin-induced deterioration in acute respiratory distress syndrome in rats

Acute Respiratory Distress Syndrome; Prostaglandins; Oleic Acid; Prostaglandin E1 Analog INTRODUCTION Acute respiratory distress syndrome (ARDS) is an inflammatory condition characterized by pulmonary edema, hypoxia, and massive influx of inflammatory cells as per the American Thoracic Society (ATS)...

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Veröffentlicht in:National journal of physiology, pharmacy and pharmacology pharmacy and pharmacology, 2017, Vol.7 (7), p.1
Hauptverfasser: Sharma, Parul, Pandey, Ratna, Deshpande, Shripad
Format: Artikel
Sprache:eng
Schlagworte:
Acids
Animals
Carotid arteries
Ethanol
Heart rate
Lungs
Mortality
Respiratory distress syndrome
Respiratory therapy
Rodents
Studies
Ventilators
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Pandey, Ratna
Deshpande, Shripad
description Acute Respiratory Distress Syndrome; Prostaglandins; Oleic Acid; Prostaglandin E1 Analog INTRODUCTION Acute respiratory distress syndrome (ARDS) is an inflammatory condition characterized by pulmonary edema, hypoxia, and massive influx of inflammatory cells as per the American Thoracic Society (ATS) guidelines. [9] The results of earlier study indicate the involvement of PGs in the pathophysiology of ARDS. [...]the present study was undertaken to identify the role of PGE1 analog in the indomethacininduced exacerbation in ARDS and to explore the possible mechanism. Protective role of prostaglandin E1 analog in indomethacininduced deterioration in acute respiratory distress syndrome in rats. Indomethacin exacerbates oleic acid induced acute respiratory distress syndrome in adult rats.
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subjects Acids
Animals
Carotid arteries
Ethanol
Heart rate
Lungs
Mortality
Respiratory distress syndrome
Respiratory therapy
Rodents
Studies
Ventilators
title Protective role of prostaglandin E1 analog in indomethacin-induced deterioration in acute respiratory distress syndrome in rats
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