Design and simulation of a flexible and ultra-sensitive biosensor based on frequency selective surface in the microwave range

In this paper, we present design and simulation of a very high sensitive biosensor based on frequency selective surface metamaterial for cancerous cells detection, in the GHz range. Split-ring resonators are used in the proposed biosensor structure because of their high sensitivities to electromagnetic waves. We have used the Cole–Cole parameters of ex vivo normal, malignant and cirrhotic cells, to do our device simulations by using Debye model. Its resolution is approximately 50 GHz, with very fine ability to separate the cancer cell types. Important advantages of our proposed biosensor are free-label, low-cost manufacturing as much as photonic crystal sensors, detection of bio-molecular composition and ultra-sensitivity. Also it can be produced locally.