Forensic Aspects of Homicides by Insulin Overdose

Highlights • This article is about research consisted of 4 actual homicidal insulin overdose cases. • In acute overdose, neuropathologic changes are not as typical as in previous hypoglycemic studies. • Severe reactive astrocyte proliferation with GFAP IHC is conspicuously found in brains of insulin...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Forensic science international 2017-09, Vol.278, p.9-15
Hauptverfasser:	Tong, Fang, Wu, Rongqi, Huang, Wen, Yang, Yi, Zhang, Lin, Zhang, Biao, Chen, Xin, Tang, Xiaohui, Zhou, Yiwu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adult Aged, 80 and over Astrocytes Astrocytes - pathology Autopsies Autopsy Brain Brain - pathology Brain damage Brain stem Case-Control Studies Cell Proliferation Cerebellum Cerebrum Clinical medicine Coma Corpus callosum Drug Overdose Female Fluorescent Antibody Technique Forensic pathology Forensic science Forensic sciences Gangrene GFAP Homicide Humans Hypoglycemia Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - poisoning Immunoassay Immunofluorescence Immunoglobulins Immunohistochemistry Inflammation Injection Injections Insulin Insulin - administration & dosage Insulin - poisoning Insulin overdose Kidney - pathology Liver - pathology Lung - pathology Male Middle Aged Myocardium - pathology Overdose Pathology Peptides Peripheral nerves Protamine Protamine sulfate Protamines - metabolism Skin Skin - metabolism Soft tissues Statistical analysis Substantia alba Suicides & suicide attempts Tissues Traumatic brain injury
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • This article is about research consisted of 4 actual homicidal insulin overdose cases. • In acute overdose, neuropathologic changes are not as typical as in previous hypoglycemic studies. • Severe reactive astrocyte proliferation with GFAP IHC is conspicuously found in brains of insulin overdose. • Presence of insulin and protamine at the injection sites is of forensic significance.
ISSN:	0379-0738 1872-6283
DOI:	10.1016/j.forsciint.2017.06.015