Replacing   agonists with antimuscarinic drugs in patients with COPD

The paper by Quint and colleagues and its linked editorial show the benefits of [beta] blockers on mortality in patients with the common combination of myocardial infarction and chronic obstructive pulmonary disease. 1 2 The competitive blockade of [beta] adrenoceptors by [beta] blockers surely negates the beneficial effects of [beta] agonists, such as salbutamol and salmeterol. Effect of [beta] blockers on mortality after myocardial infarction in adults with COPD: population based cohort study of UK electronic healthcare records.