D12 MECHANISMS OF ALLERGIC AIRWAY INFLAMMATION: Regulation Of Type 2 Innate Lymphoid Cells By Microrna-155

D12 MECHANISMS OF ALLERGIC AIRWAY INFLAMMATION: Regulation Of Type 2 Innate Lymphoid Cells By Microrna-155

Mice received bone marrow transplants from wild type (WT), miR-155 deficient and ILC2-deficient (RoRaflox/sg-IL7Cre) mice and ILC2 and their precursors quantified following treatment with IL-33. [...]to the deficit in ILC2s there were no differences in bone marrow ILC precursors (hematopoietic stem...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Knolle, M D, Englezakis, A, McKenzie, A
Format: Artikel
Sprache:eng
Schlagworte:
Bone marrow
Cytokines
Rodents
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Zusammenfassung:Mice received bone marrow transplants from wild type (WT), miR-155 deficient and ILC2-deficient (RoRaflox/sg-IL7Cre) mice and ILC2 and their precursors quantified following treatment with IL-33. [...]to the deficit in ILC2s there were no differences in bone marrow ILC precursors (hematopoietic stem cells, common lymphoid precursors, common helper innate lymphoid precursors) or in circulating ILC2 and ILC2 precursors.
ISSN:1073-449X
1535-4970