C80-B MULTI-MODALITY ASSESSMENT OF COPD, ASTHMA, AND ASTHMA-COPD OVERLAP SYNDROME: Computed Tomography Visual Emphysema Scoring And Quantitative Measurements Provide Independent And Complementary Information In COPD

Spirometry and plethysmography were performed for measurement of the forced-expiratory-volume-in-1s (FEV1, forced-vital-capacity (FVC) and diffusion-capacity-of-the-lung-for-carbon-monoxide (DLCO)- Radiologists visually scored CT emphysema on a 5-point scale. Conclusions: These findings suggest that visual emphysema scoring provides information independent of quantitative measures of lesion size, distribution or other morphological features related to COPD, further supporting the notion that visual and quantitative measures capture complementary information. The Canadian Institute of Heath Research (CIHR/Rx&D Collaborative Research Program Operating Grants93326); the Respiratory Health Network of the FRSQ; the Canadian Respiratory Research Network (CRRN); Lung Association (CLA)/Canadian Thoracic Society (CTS); British Columbia Lung Association; industry partners Astra Zeneca Canada Inc,, Boehringer-Ingelheim Canada Inc, GlaxoSmithKline Canada Inc, Merck, Novartis Pharma Canada Inc., Nycomed Canada Inc., Pfizer Canada Ltd. Dr. Kirby gratefully acknowledges postdoctoral support from the Canadian Institutes of Health Research (CIHR) Integrated and Mentored Pulmonary and Cardiovascular Training program (IMPACT) and the CIHR Banting Postdoctoral Fellowship program.