D27 I WANNA BE YOUR ... NOVEL MECHANISTIC INSIGHT INTO PULMONARY VASCULAR DISEASE: Mirna Cargo In Microvesicles Released From Hypoxic Pulmonary Arterial Endothelial Cells Induces Pulmonary Vascular Smooth Muscle Cell Proliferation And Pulmonary Hypertension

Rationale: Crosstalk between pulmonary arterial endothelial cells (PAEC) and pulmonary arterial smooth muscle cells (PASMC) plays an important role in the pathogenesis of pulmonary hypertension (PH). [...]we injected 8-week old C57BL/6 mice with DMSO control or GW4869, a drug that is known to block...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser:	Chen, T, Sun, M, Ramchandran, R, Raj, J U
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell growth Hypoxia Pathogenesis Pulmonary hypertension Smooth muscle
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!