D104 ADVANCES IN INTERSTITIAL LUNG DISEASE: Association Between Obstructive Sleep Apnea And Subclinical Interstitial Lung Disease: The MESA Sleep Study

D104 ADVANCES IN INTERSTITIAL LUNG DISEASE: Association Between Obstructive Sleep Apnea And Subclinical Interstitial Lung Disease: The MESA Sleep Study

Methods: We performed a cross-sectional analysis of 1,690 participants in the Multi-Ethnic Study of Atherosclerosis (MESA) Sleep Study, a multicenter NHLBI-funded cohort of community-dwelling adults who underwent polysomnography and chest CT imaging. Conclusions: OSA and nocturnal hypoxemia are asso...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Kim, J S, Podolanczuk, A, Borker, P, Kawut, S M, Raghu, G, Kaufman, J D, Barr, R G, Peterson, E R, Hinckley Stukovsky, K D, Hoffman, E A, Redline, S S, Lederer, D J
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers
Lung diseases
Sleep apnea
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Methods: We performed a cross-sectional analysis of 1,690 participants in the Multi-Ethnic Study of Atherosclerosis (MESA) Sleep Study, a multicenter NHLBI-funded cohort of community-dwelling adults who underwent polysomnography and chest CT imaging. Conclusions: OSA and nocturnal hypoxemia are associated with high attenuation areas on CT and with higher serum MMP-7 and SP-A in community-dwelling adults, suggesting a pathogenic role of OSA in subclinical ILD.
ISSN:1073-449X
1535-4970