D21 IMMUNE PATHWAYS IN ACUTE LUNG INJURY AND FIBROSIS: Role Of Dendritic Cells In Pulmonary Fibrosis In Mice
Methods The following mouse models were employed: 1) FMS-like tyrosine kinase-3 ligand (Flt3L) KO mice exhibiting congenital deficiency of Flt3L. 2) Chimeric zDC+/DTR mice allowing selective depletion of dendritic cells while sparing macrophages. 3) CD103 KO mice lacking the aE chain (CD103) of ß7 i...
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| Veröffentlicht in: | American journal of respiratory and critical care medicine 2017-01, Vol.195 |
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| container_title | American journal of respiratory and critical care medicine |
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| creator | Tarres, M Tort Aschenbrenner, F Maus, R Stolper, J Knudsen, L Jonnigk, D Welte, T Gauldie, J Maus, U Kolb, M |
| description | Methods The following mouse models were employed: 1) FMS-like tyrosine kinase-3 ligand (Flt3L) KO mice exhibiting congenital deficiency of Flt3L. 2) Chimeric zDC+/DTR mice allowing selective depletion of dendritic cells while sparing macrophages. 3) CD103 KO mice lacking the aE chain (CD103) of ß7 integrin. [...]CD103 deficiency did not impact on lung fibrosis after AdTGF-ß1 exposure relative to WT mice. |
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[...]CD103 deficiency did not impact on lung fibrosis after AdTGF-ß1 exposure relative to WT mice.</description><subject>Dendritic cells</subject><subject>Gene expression</subject><subject>Kinases</subject><subject>Lungs</subject><subject>Pulmonary fibrosis</subject><subject>Rodents</subject><issn>1073-449X</issn><issn>1535-4970</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNisuKwjAYhYMoeH2HH2ZdSNKq7ew6vWjEVukFdSXqRIjERhO78O0t4gO4Ouc732mhHhnbY8vxprjddDy1Lcfxtl3UN-aCMaEuwT0kQ0qAJUmZRrD2i_nG3-XAUvCDsohgWaazhhZltgM_DSFmf9kqZ_kvZEpyWJ0h5NW_Fg9xgoBLaYBVsK7lVVUH_YRYHLUy4r0m4sSHqHM-SMNHnxygnzgqgrl10-pec_PYX1Stq0btiUcn7sSlLrW_e70AeZBEEA</recordid><startdate>20170101</startdate><enddate>20170101</enddate><creator>Tarres, M Tort</creator><creator>Aschenbrenner, F</creator><creator>Maus, R</creator><creator>Stolper, J</creator><creator>Knudsen, L</creator><creator>Jonnigk, D</creator><creator>Welte, T</creator><creator>Gauldie, J</creator><creator>Maus, U</creator><creator>Kolb, M</creator><general>American Thoracic Society</general><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20170101</creationdate><title>D21 IMMUNE PATHWAYS IN ACUTE LUNG INJURY AND FIBROSIS: Role Of Dendritic Cells In Pulmonary Fibrosis In Mice</title><author>Tarres, M Tort ; 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| ispartof | American journal of respiratory and critical care medicine, 2017-01, Vol.195 |
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| language | eng |
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| source | American Thoracic Society Journals; Journals@Ovid Complete; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Dendritic cells Gene expression Kinases Lungs Pulmonary fibrosis Rodents |
| title | D21 IMMUNE PATHWAYS IN ACUTE LUNG INJURY AND FIBROSIS: Role Of Dendritic Cells In Pulmonary Fibrosis In Mice |
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