C38 UNDERSTANDING THERAPEUTICS IN IPF: Risk Factors Associated With Pirfenidone Discontinuation In Patients With Idiopathic Pulmonary Fibrosis In A Real-World Setting

C38 UNDERSTANDING THERAPEUTICS IN IPF: Risk Factors Associated With Pirfenidone Discontinuation In Patients With Idiopathic Pulmonary Fibrosis In A Real-World Setting

Stepwise logistic regression models were used to determine the odds of discontinuing treatment within the first six months due to adverse drug reactions (ADRs) as a function of baseline patient characteristics. Using stepwise logistic regression, patient characteristics found to be associated with s...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Cottin, V, Guenther, A, Albera, C, Tomassetti, S, Azuma, A, Bartley, K, Burgess, T, Odueyungbo, A, Kirchgaessler, K-U, Maher, T M
Format: Artikel
Sprache:eng
Schlagworte:
Chronic obstructive pulmonary disease
Patients
Pulmonary fibrosis
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Zusammenfassung:Stepwise logistic regression models were used to determine the odds of discontinuing treatment within the first six months due to adverse drug reactions (ADRs) as a function of baseline patient characteristics. Using stepwise logistic regression, patient characteristics found to be associated with significantly increased odds of discontinuing pirfenidone due to an ADR within six months were: older age (odds ratio [OR]=1.07 for each year of age, p
ISSN:1073-449X
1535-4970