C21 OMICS IN LUNG DISEASE: Whole Genome Sequencing Study On Bronchodilator Drug Response In Ethnically Diverse Children With Asthma

Despite significant racial/ethnic variation in bronchodilator drug response (BDR), albuterol is often the only medication prescribed for asthma, regardless of disease severity. Methods We performed whole genome sequencing on 1,500 ethnically diversed children with asthma from the extremes of broncho...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Mak, A, White, M J, Szpiech, Z A, Eckalbar, W, Pino-Yanes, M, Oh, S, Hu, D, Huntsman, S, Eng, C, Davis, A, Serebrisky, D, Brigino-Buenaventura, E, Lurmann, F, Farber, H J, Rodriguez-Santana, J R, Meade, K, Borrell, L N, LeNoir, M A, Avila, P C, Kumar, R, Sen, S, Thyne, S, Rodriguez-Cintron, W, Kwok, P-Y, Torgerson, D G, Galanter, J, Ahituv, N, Ziv, E, Seibold, M A, Zaitlen, N, Hernandez, R D, Burchard, E G
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container_title American journal of respiratory and critical care medicine
container_volume 195
creator Mak, A
White, M J
Szpiech, Z A
Eckalbar, W
Pino-Yanes, M
Oh, S
Hu, D
Huntsman, S
Eng, C
Davis, A
Serebrisky, D
Brigino-Buenaventura, E
Lurmann, F
Farber, H J
Rodriguez-Santana, J R
Meade, K
Borrell, L N
LeNoir, M A
Avila, P C
Kumar, R
Sen, S
Thyne, S
Rodriguez-Cintron, W
Kwok, P-Y
Torgerson, D G
Galanter, J
Ahituv, N
Ziv, E
Seibold, M A
Zaitlen, N
Hernandez, R D
Burchard, E G
description Despite significant racial/ethnic variation in bronchodilator drug response (BDR), albuterol is often the only medication prescribed for asthma, regardless of disease severity. Methods We performed whole genome sequencing on 1,500 ethnically diversed children with asthma from the extremes of bronchodilator drug response to albuterol.
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identifier ISSN: 1073-449X
ispartof American journal of respiratory and critical care medicine, 2017-01, Vol.195
issn 1073-449X
1535-4970
language eng
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source American Thoracic Society (ATS) Journals Online; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection; Journals@Ovid Complete
subjects Asthma
Bronchodilators
Genomes
Population
title C21 OMICS IN LUNG DISEASE: Whole Genome Sequencing Study On Bronchodilator Drug Response In Ethnically Diverse Children With Asthma
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