C98 HOT THINGS: INFLAMMATION, REMODELING, AND SYSTEMIC DISEASE IN PULMONARY HYPERTENSION: Activated Conventional Dendritic Cells As Drivers In The Pathophysiology Of Idiopathic Pulmonary Arterial Hypertension (ipah)?

C98 HOT THINGS: INFLAMMATION, REMODELING, AND SYSTEMIC DISEASE IN PULMONARY HYPERTENSION: Activated Conventional Dendritic Cells As Drivers In The Pathophysiology Of Idiopathic Pulmonary Arterial Hypertension (ipah)?

Pulmonary vessels in the lungs of 31w Tnfaip3DNGR1-KO mice exhibited remodeling, e.g. smooth muscle wall thickening and collagen deposition, and increased perivascular infiltration resembling TLOs. [...]investigating DC activation in the development and/or progression of PAH will be valuable to gain...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Koudstaal, T, Van Hulst, J, Das, T, Heukels, P, Merkus, D, De Raaf, M, Bergen, I, Bogaard, H, Sousa, C Reis E, VanLoo, G, Hendriks, R, Boomars, K, Kool, M
Format: Artikel
Sprache:eng
Schlagworte:
Cytokines
Dendritic cells
Hypertension
Lungs
Rodents
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Zusammenfassung:Pulmonary vessels in the lungs of 31w Tnfaip3DNGR1-KO mice exhibited remodeling, e.g. smooth muscle wall thickening and collagen deposition, and increased perivascular infiltration resembling TLOs. [...]investigating DC activation in the development and/or progression of PAH will be valuable to gain more insight in the mechanisms driving the pathophysiology of IPAH.
ISSN:1073-449X
1535-4970