C80-B MULTI-MODALITY ASSESSMENT OF COPD, ASTHMA, AND ASTHMA-COPD OVERLAP SYNDROME: Small Airways Impairment In Severe Asthmatic Patients With Fixed Airflow Obstruction And In COPD

C80-B MULTI-MODALITY ASSESSMENT OF COPD, ASTHMA, AND ASTHMA-COPD OVERLAP SYNDROME: Small Airways Impairment In Severe Asthmatic Patients With Fixed Airflow Obstruction And In COPD

Extensive lung function tests, Single Breath Nitrogen Washout Test (SBNWT) and Impulse Oscillometry (iOS) were performed at each visit. Results: The inhomogeneity of small airways ventilation was evaluated by the slope of phase 3 measured at SBNWT (dN2) while the contribution of small airways resist...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Contoli, M, Morandi, L, Bellini, F, Soave, S, ini, G, Pauletti, A, Marchi, M, Marchi, I, Caramori, G, Papi, A
Format: Artikel
Sprache:eng
Schlagworte:
Air flow
Asthma
Chronic obstructive pulmonary disease
Health risk assessment
Patients
Smoking cessation
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Zusammenfassung:Extensive lung function tests, Single Breath Nitrogen Washout Test (SBNWT) and Impulse Oscillometry (iOS) were performed at each visit. Results: The inhomogeneity of small airways ventilation was evaluated by the slope of phase 3 measured at SBNWT (dN2) while the contribution of small airways resistance to total airflow resistance was assessed by iOS (R5-R20). dN2 and R5-R20 levels were significantly higher in AFAO patients compare to asthmatic patients with fully reversible airflow obstruction (p
ISSN:1073-449X
1535-4970