C105 DISORDERS OF RESPIRATORY PHYSIOLOGY AND SLEEP IN CHILDREN: High Altitude Worsens Obstructive And Central Sleep Apnea In Children: A Crossover Trial Of High Altitude Dwellers

Methods: We performed a crossover trial comparing high altitude home polysomnography (H-PSG) performed at 2108-3124 masl with lower altitude laboratory polysomnography (L-PSG) performed in Denver, Colorado (1600 masl). Amongst school-age children suspected of having OSA and dwelling at high altitude, laboratory PSG at lower altitude consistently underestimates disease presence and severity compared to home PSG. [...]oxygenation is worse and arousal frequency increased at the home altitude.