D97 IMPACT OF INFLAMMATION ON ACUTE LUNG INJURY: Uptake Of Cell-Free Hemoglobin Impairs Cytokine Production By Macrophages

D97 IMPACT OF INFLAMMATION ON ACUTE LUNG INJURY: Uptake Of Cell-Free Hemoglobin Impairs Cytokine Production By Macrophages

Rationale: Cell-free hemoglobin (CFH) is elevated in the airspace during acute lung injury and is associated with increased inflammation. Preliminary data showing that supplemental haptoglobin improves CFH uptake suggests that haptoglobin could be a novel therapy for attenuation of acute lung injury...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Shaver, C M, Landstreet, S R, Putz, N, Hubler, M J, Hasty, A H, Ware, L B, Bastarache, J A
Format: Artikel
Sprache:eng
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Cytokines
Inflammation
Microscopy
Rodents
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container_title American journal of respiratory and critical care medicine
container_volume 195
creator Shaver, C M
Landstreet, S R
Putz, N
Hubler, M J
Hasty, A H
Ware, L B
Bastarache, J A
description Rationale: Cell-free hemoglobin (CFH) is elevated in the airspace during acute lung injury and is associated with increased inflammation. Preliminary data showing that supplemental haptoglobin improves CFH uptake suggests that haptoglobin could be a novel therapy for attenuation of acute lung injury.
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source American Thoracic Society Journals; Journals@Ovid Complete; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Cytokines
Inflammation
Microscopy
Rodents
title D97 IMPACT OF INFLAMMATION ON ACUTE LUNG INJURY: Uptake Of Cell-Free Hemoglobin Impairs Cytokine Production By Macrophages
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