C32 LUNG INJURY, ARDS, AND SEPSIS: Early Vascular Events Are Associated With Development Of Ards

C32 LUNG INJURY, ARDS, AND SEPSIS: Early Vascular Events Are Associated With Development Of Ards

Patients were screened in the emergency department of 16 US academic hospitals for enrollment in the Lung Injury Prevention Study with Aspirin (LIPS-A), a randomized, multicenter, double-blind clinical trial of aspirin or placebo in patients at risk for ARDS. Plasma concentrations of thromboxane B2...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Abdulnour, R E, Gunderson, T, Barkas, I, Timmons, J Y, Barnig, C, Gong, M N, Kor, D J, Gajic, O, Talmor, D, Carter, R, Levy, B D
Format: Artikel
Sprache:eng
Schlagworte:
Aspirin
Blood platelets
Neutrophils
Pathogenesis
Sepsis
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Zusammenfassung:Patients were screened in the emergency department of 16 US academic hospitals for enrollment in the Lung Injury Prevention Study with Aspirin (LIPS-A), a randomized, multicenter, double-blind clinical trial of aspirin or placebo in patients at risk for ARDS. Plasma concentrations of thromboxane B2 (TxB2) and aspirin-triggered lipoxin A4 (ATL), and peripheral blood leukocyte number and activation (leukocyte-platelet aggregates, CD11b surface expression) were determined.
ISSN:1073-449X
1535-4970