A14 COPD: SYSTEMS BIOLOGY AND COMORBIDITY: Lung Health And The Association With Cardiovascular Disease Outcomes: The Cardia Study

A14 COPD: SYSTEMS BIOLOGY AND COMORBIDITY: Lung Health And The Association With Cardiovascular Disease Outcomes: The Cardia Study

Methods: We used Cox proportional hazards regression to assess the association between pulmonary function at the baseline exam in 1985 with fatal and nonfatal cardiovascular events over 27 years of follow up. When traditional cardiovascular risk factors, diabetes, total cholesterol, and systemic blo...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Cuttica, M J, Colangelo, L A, Washko, G, Carr, J J, Rana, J, Jacobs, D R, Thyagarajan, B, Sidney, S, Lewis, C E, Liu, K, Lloyd-Jones, D, Kalhan, R
Format: Artikel
Sprache:eng
Schlagworte:
Age
Blood pressure
Cardiovascular disease
Chronic obstructive pulmonary disease
Comorbidity
Diabetes
Health risk assessment
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Zusammenfassung:Methods: We used Cox proportional hazards regression to assess the association between pulmonary function at the baseline exam in 1985 with fatal and nonfatal cardiovascular events over 27 years of follow up. When traditional cardiovascular risk factors, diabetes, total cholesterol, and systemic blood pressure, were added into the multivariate model FEV1 (HR 0.60 [0.45, 0.81], p=0.0008) and FVC (HR 0.66, [0.50, 0.86], p=0.0025) at mean age 25 remain independent predictors of future cardiovascular disease events.
ISSN:1073-449X
1535-4970