D30 NEW INSIGHTS INTO OBSTRUCTIVE SLEEP APNEA PATHOGENESIS: Effects Of Hypnotics On The Phenotypic Causes Of Obstructive Sleep Apnea

D30 NEW INSIGHTS INTO OBSTRUCTIVE SLEEP APNEA PATHOGENESIS: Effects Of Hypnotics On The Phenotypic Causes Of Obstructive Sleep Apnea

Despite the high prevalence of hypnotic use (>5% of the adult population), data on the effects of hypnotics on the phenotypic causes of OSA (arousal threshold, muscle responsiveness and upper airway collapsibility) are limited. Conclusions: Standard doses of common hypnotics increase the respirat...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Carberry, J C, Fisher, L P, Grunstein, R R, Gandevia, S C, McKenzie, D K, Butler, J E, Eckert, D J
Format: Artikel
Sprache:eng
Schlagworte:
Muscle function
Sleep
Sleep apnea
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Zusammenfassung:Despite the high prevalence of hypnotic use (>5% of the adult population), data on the effects of hypnotics on the phenotypic causes of OSA (arousal threshold, muscle responsiveness and upper airway collapsibility) are limited. Conclusions: Standard doses of common hypnotics increase the respiratory arousal threshold albeit to different extents without reducing upper airway muscle activity or airway collapsibility during sleep.
ISSN:1073-449X
1535-4970