A74 REGULATORY MECHANISMS OF THE MOLECULAR PATHWAYS IN FIBROSIS: Circulating Desmosine Levels In Idiopathic Pulmonary Fibrosis And Chronic Obstructive Pulmonary Disease

A74 REGULATORY MECHANISMS OF THE MOLECULAR PATHWAYS IN FIBROSIS: Circulating Desmosine Levels In Idiopathic Pulmonary Fibrosis And Chronic Obstructive Pulmonary Disease

Introduction: Although chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) are different from a clinical perspective, common initial pathogenic steps have been suggested in both lung diseases. Methods: bDES levels were measured by a liquid chromatography-tandem mass...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Robberts, B, Drent, M, Spanbroek, M, Van Den Ouweland, J M, Zanen, P, Van Moorsel, C H M, Wijnen, P A, Janssens, W, Janssen, R
Format: Artikel
Sprache:eng
Schlagworte:
Chronic obstructive pulmonary disease
Lung diseases
Pulmonary fibrosis
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Zusammenfassung:Introduction: Although chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) are different from a clinical perspective, common initial pathogenic steps have been suggested in both lung diseases. Methods: bDES levels were measured by a liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay in 79 IPF patients, 142 patients with moderate to severe COPD and 84 controls.
ISSN:1073-449X
1535-4970