C51 CRITICAL CARE: MORE NON-PULMONARY CRITICAL CARE PROBLEMS: Antidotal Effects Of Methylene Blue During Lethal Forms Of Cyanide Poisoning

C51 CRITICAL CARE: MORE NON-PULMONARY CRITICAL CARE PROBLEMS: Antidotal Effects Of Methylene Blue During Lethal Forms Of Cyanide Poisoning

In 10 urethane-anesthetized rats, cyanide (KCN) was infused i.v. at the rate of 0.75 mg/kg/min, which we previously found to lead to a pulseless electrical activity within 7 minutes. MB allowed a rapid restoration of arterial blood pressure by the end of exposure to CN, while cardiac contractility w...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Haouzi, P, Sonobe, T, Tubbs, N
Format: Artikel
Sprache:eng
Schlagworte:
Blood pressure
Critical care
Rodents
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Zusammenfassung:In 10 urethane-anesthetized rats, cyanide (KCN) was infused i.v. at the rate of 0.75 mg/kg/min, which we previously found to lead to a pulseless electrical activity within 7 minutes. MB allowed a rapid restoration of arterial blood pressure by the end of exposure to CN, while cardiac contractility was maintained.
ISSN:1073-449X
1535-4970