A13 ROLE OF DYSBIOSIS IN LUNG DISEASE: Lung Cancer And Lung Microbiome

Rationale Lung cancer continues to be the leading cause of cancer deaths in the U.S. Lower airway immunological phenotypes may be important for immune surveillance in lung cancer. Oral brushing, protected proximal airway and distal airway brushing were obtained, and 16S rRNA gene V4 region sequencin...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Tsay, J J, Clemente, J, Lhakhang, T, Li, Y, Yie, T-A, Wu, B G, Kapoor, B, Wang, J, Sterman, D H, Heguy, A, Rom, W N, Blaser, M, Segal, L N
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Sprache:eng
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Zusammenfassung:Rationale Lung cancer continues to be the leading cause of cancer deaths in the U.S. Lower airway immunological phenotypes may be important for immune surveillance in lung cancer. Oral brushing, protected proximal airway and distal airway brushing were obtained, and 16S rRNA gene V4 region sequencing was performed with MiSeq, taxonomy assigned with QIIME, and taxonomic differences evaluated with LEfSe.
ISSN:1073-449X
1535-4970