D26 LUNG DEVELOPMENT AND BPD: Lymphocyte Expression Biomarkers Of Chronic Lung Diseases Following Preterm Birth

D26 LUNG DEVELOPMENT AND BPD: Lymphocyte Expression Biomarkers Of Chronic Lung Diseases Following Preterm Birth

Methods: Transcriptomic profiles were generated from sorted CD8+ T lymphocytes obtained from peripheral blood collected at the time of first hospital discharge, from preterm and full-term infants enrolled in the NHLBI Prematurity and Respiratory Outcomes Program (PROP) at the University of Rochester...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Bhattacharya, S, Mereness, J, Baran, A, Misra, R S, Slaunwhite, C, Huyck, H, Bandyopadhyay, S, Holden-Wiltse, J, Peterson, D R, Ryan, R M, Reynolds, A-M, Pryhuber, G S, Mariani, T J
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers
Disease
Gene expression
Lymphocytes
Newborn babies
Premature birth
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Zusammenfassung:Methods: Transcriptomic profiles were generated from sorted CD8+ T lymphocytes obtained from peripheral blood collected at the time of first hospital discharge, from preterm and full-term infants enrolled in the NHLBI Prematurity and Respiratory Outcomes Program (PROP) at the University of Rochester and the University at Buffalo (n=145). Summary: Gene expression from peripheral blood lymphocytes can predict respiratory outcomes in preterm infants and provides novel information on disease processes associated with disease states.
ISSN:1073-449X
1535-4970