C80-C IMAGING METHODOLOGY AND APPLICATION TO LUNG DISEASE: Regional Comparison Of Vascular Volume Measured On CT With Ventilation Defect Percent On Hyperpolarized Helium-3 Mri In Asthma

Corresponding author's email: mummy@wisc.edu Rationale: Ventilation defects have been observed in asthma patients using the distribution of hyperpolarized helium-3 (HP 3He) MRI and quantified as a local marker of airway obstruction using the segmental ventilation defect percent (SVDP) (Thomen e...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Mummy, D, Rahaghi, F N, Zha, W, Ross, J, Denlinger, L C, Jarjour, N N, Estepar, R San Jose, Washko, G, Fain, S B
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Sprache:eng
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Zusammenfassung:Corresponding author's email: mummy@wisc.edu Rationale: Ventilation defects have been observed in asthma patients using the distribution of hyperpolarized helium-3 (HP 3He) MRI and quantified as a local marker of airway obstruction using the segmental ventilation defect percent (SVDP) (Thomen et al. 2014). A linear mixed-effects model was used to model segmental small-vessel percent with SVDP, disease severity, body-mass index (BMI), age, gender, and segment ID as fixed effects, and subject ID as a random effect.
ISSN:1073-449X
1535-4970