C67 SUPPURATIVE LUNG DISEASES IN CHILDREN: Application Of Pharmacokinetics And Pharmacodynamics To Determine Dose Optimization Using Beta Lactams In Pediatric Cystic Fibrosis Population
Rationale: Acute and chronic bacterial infections cause acute pulmonary exacerbations (APE) with tremendous morbidity and mortality in patients with cystic fibrosis (CF). CF patients could benefit from therapeutic drug monitoring to improve beta lactam antibiotic exposure and clinical outcomes, espe...
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Veröffentlicht in: | American journal of respiratory and critical care medicine 2017-01, Vol.195 |
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container_title | American journal of respiratory and critical care medicine |
container_volume | 195 |
creator | Jensen, C Fanous, H Chaney, H R Sami-Zakhari, I R Perez, G F Louie, S Hahn, A |
description | Rationale: Acute and chronic bacterial infections cause acute pulmonary exacerbations (APE) with tremendous morbidity and mortality in patients with cystic fibrosis (CF). CF patients could benefit from therapeutic drug monitoring to improve beta lactam antibiotic exposure and clinical outcomes, especially when treating antibiotic resistant organisms. |
format | Article |
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language | eng |
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source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Ovid Autoload; American Thoracic Society (ATS) Journals Online; Alma/SFX Local Collection |
subjects | Antibiotics Cystic fibrosis Drug dosages Pediatrics Pharmacodynamics Pharmacokinetics Therapeutic drug monitoring |
title | C67 SUPPURATIVE LUNG DISEASES IN CHILDREN: Application Of Pharmacokinetics And Pharmacodynamics To Determine Dose Optimization Using Beta Lactams In Pediatric Cystic Fibrosis Population |
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