C67 SUPPURATIVE LUNG DISEASES IN CHILDREN: Application Of Pharmacokinetics And Pharmacodynamics To Determine Dose Optimization Using Beta Lactams In Pediatric Cystic Fibrosis Population

Rationale: Acute and chronic bacterial infections cause acute pulmonary exacerbations (APE) with tremendous morbidity and mortality in patients with cystic fibrosis (CF). CF patients could benefit from therapeutic drug monitoring to improve beta lactam antibiotic exposure and clinical outcomes, espe...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Jensen, C, Fanous, H, Chaney, H R, Sami-Zakhari, I R, Perez, G F, Louie, S, Hahn, A
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container_title American journal of respiratory and critical care medicine
container_volume 195
creator Jensen, C
Fanous, H
Chaney, H R
Sami-Zakhari, I R
Perez, G F
Louie, S
Hahn, A
description Rationale: Acute and chronic bacterial infections cause acute pulmonary exacerbations (APE) with tremendous morbidity and mortality in patients with cystic fibrosis (CF). CF patients could benefit from therapeutic drug monitoring to improve beta lactam antibiotic exposure and clinical outcomes, especially when treating antibiotic resistant organisms.
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source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Journals@Ovid Ovid Autoload; American Thoracic Society (ATS) Journals Online; Alma/SFX Local Collection
subjects Antibiotics
Cystic fibrosis
Drug dosages
Pediatrics
Pharmacodynamics
Pharmacokinetics
Therapeutic drug monitoring
title C67 SUPPURATIVE LUNG DISEASES IN CHILDREN: Application Of Pharmacokinetics And Pharmacodynamics To Determine Dose Optimization Using Beta Lactams In Pediatric Cystic Fibrosis Population
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