C67 SUPPURATIVE LUNG DISEASES IN CHILDREN: Application Of Pharmacokinetics And Pharmacodynamics To Determine Dose Optimization Using Beta Lactams In Pediatric Cystic Fibrosis Population

C67 SUPPURATIVE LUNG DISEASES IN CHILDREN: Application Of Pharmacokinetics And Pharmacodynamics To Determine Dose Optimization Using Beta Lactams In Pediatric Cystic Fibrosis Population

Rationale: Acute and chronic bacterial infections cause acute pulmonary exacerbations (APE) with tremendous morbidity and mortality in patients with cystic fibrosis (CF). CF patients could benefit from therapeutic drug monitoring to improve beta lactam antibiotic exposure and clinical outcomes, espe...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Hauptverfasser: Jensen, C, Fanous, H, Chaney, H R, Sami-Zakhari, I R, Perez, G F, Louie, S, Hahn, A
Format: Artikel
Sprache:eng
Schlagworte:
Antibiotics
Cystic fibrosis
Drug dosages
Pediatrics
Pharmacodynamics
Pharmacokinetics
Therapeutic drug monitoring
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Zusammenfassung:Rationale: Acute and chronic bacterial infections cause acute pulmonary exacerbations (APE) with tremendous morbidity and mortality in patients with cystic fibrosis (CF). CF patients could benefit from therapeutic drug monitoring to improve beta lactam antibiotic exposure and clinical outcomes, especially when treating antibiotic resistant organisms.
ISSN:1073-449X
1535-4970