Stereoselective Vicinal Difunctionalization of Alkynes through a Three‐Component Reaction of Alkynes, Sodium Sulfinates, and Togni Reagent

Stereoselective vicinal difunctionalization of alkynes through trifluoromethylation and sulfonylation via a three‐component reaction of alkynes, sodium sulfinates, and Togni reagent under catalyst‐ and additive‐free conditions has been realized. This reaction proceeds at room temperature in dimethyl sulfoxide (DMSO), providing (E)‐β‐trifluoromethylvinyl sulfones in moderate to good yields. The advantages of this tandem radical process include extremely mild conditions, excellent stereoselectivity, and easy experimental operation.