A schistosomiasis compartment model with incubation and its optimal control

A new mathematical model included an exposed compartment is established in consideration of incubation period of schistosoma in human body. The basic reproduction number is calculated to illustrate the threshold of disease outbreak. The existence of the disease free equilibrium and the endemic equil...

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Veröffentlicht in:Mathematical methods in the applied sciences 2017-09, Vol.40 (14), p.5079-5094
Hauptverfasser: Ding, Chunxiao, Sun, Yun, Zhu, Yuanguo
Format: Artikel
Sprache:eng
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Zusammenfassung:A new mathematical model included an exposed compartment is established in consideration of incubation period of schistosoma in human body. The basic reproduction number is calculated to illustrate the threshold of disease outbreak. The existence of the disease free equilibrium and the endemic equilibrium are proved. Studies about stability behaviors of the model are exploited. Moreover, control measure assessments are investigated in order to seek out effective control interventions for anti‐schistosomiasis. Then, the corresponding optimal control problem according to the model is presented and solved. Theoretical analyses and numerical simulations induce several prevention and control strategies for anti‐schistosomiasis. At last, a discussion is provided about our results and further work. Copyright © 2017 John Wiley & Sons, Ltd.
ISSN:0170-4214
1099-1476
DOI:10.1002/mma.4372