Morphological Changes In Mucous Membrane Of Bronchi In Patients With Severe Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) and in the twenty-first century remains a major global health problem, resulting high rates of morbidity and mortality. In the past two decades important progress has been made in the understanding of the epidemiology, pathophysiology, diagnosis, and treatment of COPD, but still there is a lack of fundamental knowledge about the cellular, molecular and genetic causes of disease. Remodeling of respiratory tracts is a pathologic process observed at chronic inflammatory and obstructive diseases of respiratory tracts. For the study 9 people with severe COPD with the periods of 1, 3 and 6 months were performed biopsies of the mucous membrane of the bronchi. Verification of the diagnosis and its formulation confirmed with the orders of Ministry of Health of Ukraine № 128 from 19.03.2007. "On approval of clinical protocols of medical care in the specialty pulmonology".