MicroRNA expression and potential linkage to the main molecular pathways of inflammation in the colonic mucosa of pediatric patients with eosinophil colitis

MicroRNA expression and potential linkage to the main molecular pathways of inflammation in the colonic mucosa of pediatric patients with eosinophil colitis

Real-time reverse transcription PCR was carried out on fresh-frozen biopsy specimen from young children with EC (EC, n=14) and control patients (C, n=10). Bioinformatics analysis of EC-related miR-target interactions revealed functional groups connected to inflammation, leukocyte activation, leukocy...

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Veröffentlicht in:Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2017-07, Vol.17 (3), p.S118-S119
Hauptverfasser: Kiss, Zoltán, Béres, Nóra Judit, Tél, Bálint, Veres, Gábor
Format: Artikel
Sprache:eng
Schlagworte:
Apoptosis
Bioinformatics
Biopsy
Cell activation
Children
Colitis
Colon
Endocrinology & Metabolism
Gastroenterology and Hepatology
Inflammatory bowel disease
Leukocytes (eosinophilic)
miRNA
Mucosa
Pediatrics
Polymerase chain reaction
Reverse transcription
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Zusammenfassung:Real-time reverse transcription PCR was carried out on fresh-frozen biopsy specimen from young children with EC (EC, n=14) and control patients (C, n=10). Bioinformatics analysis of EC-related miR-target interactions revealed functional groups connected to inflammation, leukocyte activation, leukocyte trafficking and the regulation of apoptosis.
ISSN:1424-3903
1424-3911
DOI:10.1016/j.pan.2017.05.373