A Reliable and Accurate Algorithm to Quantify the Tumor Stroma (QTS) across Tumor Entities

A Reliable and Accurate Algorithm to Quantify the Tumor Stroma (QTS) across Tumor Entities

Immunohistochemistry of CD3 and CD8 antigens in metastatic colorectal cancer (mCRC), ovarian cancer (OvCa), hepatocellular carcinoma (HCC), and pancreatic cancer (PDAC) was performed (N=80). To examine whether quantification of 1 vs 3 hot spots yields accurate results, CD8+/CD3+ ratio as well as the...

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Veröffentlicht in:Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2017-07, Vol.17 (3), p.S43-S43
Hauptverfasser: Miksch, Rainer Christoph, Weniger, Maximilian, Hao, Jingcheng, Dötzer, Katharina, Schlüter, Friederike, Yin, Shuai, Ormanns, Steffen, Mayer, Barbara, Schoenberg, Markus B, Bazhin, Alexandr V, Werner, Jens, D'Haese, Jan G
Format: Artikel
Sprache:eng
Schlagworte:
Algorithms
Antigens
Cancer
CD3 antigen
CD8 antigen
Colorectal carcinoma
Endocrinology & Metabolism
Gastroenterology and Hepatology
Hepatocellular carcinoma
Immunohistochemistry
Metastases
Ovarian cancer
Pancreatic cancer
Pancreatic carcinoma
Stroma
Studies
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Zusammenfassung:Immunohistochemistry of CD3 and CD8 antigens in metastatic colorectal cancer (mCRC), ovarian cancer (OvCa), hepatocellular carcinoma (HCC), and pancreatic cancer (PDAC) was performed (N=80). To examine whether quantification of 1 vs 3 hot spots yields accurate results, CD8+/CD3+ ratio as well as the absolute cell numbers were compared using intraclass-correlation...
ISSN:1424-3903
1424-3911
DOI:10.1016/j.pan.2017.05.133